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SMITHERS, BRITISH COLUMBIA - APRIL 24: Brenda Wilson comforts her mother, Matilda, as she describes wanting to kill herself after discovering that her daughter Ramona had disappeared in 1994, April 24, 2016 in Smithers, British Columbia. Ramona Wilson had left for a dance a few towns away along highway 16, and never came home. Her body was discovered several months later. Canadaâs Route 16, which connects Prince George with Prince Rupert and runs for 450 miles through the province of British Columbia, has been given the nickname of the Highway of Tears. Along this east to west road, it is estimated that as many as forty First Nations women and girls have been murdered or disappeared. Across Canada, it is estimated that between 1980 and 2014, as many as 1,200 native women and girls were murdered or vanished. (Photo by Andrew Lichtenstein/ Corbis via Getty Images)